Lionel Messi is the obvious play for Tuesday's match between Barcelona and Leganes, but RotoWire's Juan Pablo Aravena has a number of other attackers that need heavy consideration.
Venezuela beat the United States 3-0 last week, and they'll look for Salomon Rondon to continue the momentum Saturday against Peru.
Paris Saint-Germain are heavy favorites away to St. Etienne on Friday, and with Neymar still sidelined due to injury, Edinson Cavani will continue to shoulder a bigger scoring load.
Lionel Messi is unavailable for Saturday's match against Malaga, which means fantasy players won't necessarily have their guaranteed goal.
Inter Milan will be without Mauro Icardi and Ivan Perisic on Saturday, which could open up some value plays as they travel to take on Genoa.
Guingamp have four clean sheets in their last five Ligue 1 matches, and they'll look to do it again Friday against Strasbourg.
Brazil and Argentina highlight Thursday's four-game CONMEBOL World Cup qualifying slate, but Andrew Laird explains why fantasy players may want to look elsewhere for big fantasy scores.
There haven't been many goals in the first four matches of Copa America, and while there may not be many fireworks Sunday, there are still plenty of fantasy points to be had.